The hotel began operation formally on January, 1921. It was the site of the Academy Awards six times and the June 1968 assassination of presidential candidate Robert F. Kennedy. The hotel closed to guests in 1989.
The Ambassador Hotel was located at 3400 Wilshire Boulevard, between Catalina Street and Mariposa Avenue in what is now known as Koreatown. It was designed by Pasadena architect Myron Hunt in an eclectic Mediterranean Revival style with Art Deco elements and signage.